Crystal structure of P. vivax geranylgeranyl diphosphate synthase complexed with BPH-811
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Crystal structure of P. vivax geranylgeranyl diphosphate synthase complexed with BPH-811 Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, SULFATE ION, ... Authors: No, J.H, Liu, Y.-L, Zhang, Y, Oldfield, E. Deposit date: 2011-05-11 Release date: 2012-05-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proc.Natl.Acad.Sci.USA, 109, 2012
创建时间:
2011-05-11



