five

Model.

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Figshare2016-02-23 更新2026-04-29 收录
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Autocrine stimulation of VHL negative ccRCC tumor cells by Activin B reduces RhoA activity thereby reorganizing the actin cytoskeleton and inducing invasiveness of spindle-shaped cells. Serum, which promotes RhoA activity, counteracts Activin B mediated effects. Rac1 activation by an unknown mechanism plays an opposite role to RhoA and is required for the invasive phenotype.
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2016-02-23
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