Bridging the analog divide: A comparison of printed X-ray films and digital images when using computer-aided detection software for tuberculosis screening

Computer-aided detection (CAD) software provides scalable, standardized chest X-ray (CXR) interpretation, helping address the global shortage of radiologists and inter-reader variability. Printed X-ray films remain common in many low-resource settings, yet most CAD software can only process Digital Imaging and Communications in Medicine (DICOM) files. Genki software (DeepTek, India) is one of the few World Health Organization (WHO)-recommended CAD software capable of interpreting both DICOM files and photographs of printed X-ray films (Joint Photographic Experts Group [JPEG] files), but its performance using JPEG files has not been independently evaluated. We evaluated Genki software using a test library of 1,466 CXR images of adults collected during mobile CXR screening for tuberculosis (TB) in Ho Chi Minh City, Viet Nam. Each test library participant’s TB status was determined using a composite reference standard, based on radiological findings and Xpert MTB/RIF Ultra testing. Ea..., , # Bridging the analog divide: A comparison of printed X-ray films and digital images when using computer-aided detection software for tuberculosis screening

Dataset DOI: [10.5061/dryad.280gb5n3f](https://doi.org/10.5061/dryad.280gb5n3f)

## Description of the data and file structure

This dataset was generated to support an independent evaluation of the Genki computer-aided detection (CAD) software (DeepTek, India) for chest X-ray (CXR) interpretation during tuberculosis (TB) screening. Data were collected during 133 mobile CXR screening events conducted across five districts in Ho Chi Minh City, Viet Nam, between July 2022 and March 2023.

The de-identified dataset includes records from 1,466 adult participants. Each participant’s TB status was determined using a composite reference standard that combined radiological interpretations with Xpert MTB/RIF Ultra assay results. Each participant’s CXR image was blindly re-read by 10 TB clinicians and processed twice using the Genki CAD soft..., The mobile CXR screening implementation was approved by the Ho Chi Minh City People’s Committee (Decision No. 2681/QĐ-UBND). Since this activity is within the Vietnamese Ministry of Health’s TB screening and treatment guidelines (Decision No. 1314/QĐ-BYT), only verbal consent was obtained from participants. The Pham Ngoc Thach Hospital Institutional Review Board reviewed and approved the protocol for this de-identified, retrospective CAD software evaluation (Decision No. 1688/HĐĐĐ-PNT).