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Cytotoxic evaluation of natural and synthetic callipeltins: a revision of cytotoxicity of callipeltin B

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DataCite Commons2020-09-04 更新2024-07-25 收录
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https://tandf.figshare.com/articles/dataset/Cytotoxic_evaluation_of_natural_and_synthetic_callipeltins_a_revision_of_cytotoxicity_of_callipeltin_B/3022909/1
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资源简介:
The cytotoxic evaluation of natural and synthetic callipeltins is described. Cyclic depsipeptide callipeltin B and linear peptides callipeltins E and M synthesized by us showed no cytotoxic activity. In contrast, natural callipeltin B purified from <i>Callipelta</i> sp. showed CC<sub>50</sub> = 130 μM against Hela cells. We found that purified callipeltin B included the contamination of callipeltins C and H at a ratio of approximately 15%. These results suggested that the cytotoxicity of natural callipeltin B was derived from callipeltins C and H.
提供机构:
Taylor & Francis
创建时间:
2016-02-29
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