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Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946

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Protein Data Bank Japan2024-03-20 更新2026-06-30 收录
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Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946 Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-[(6-aminopyridin-2-yl)methyl]-4-methyl-2-[(1H-pyrazol-3-yl)methyl]-4,6-dihydro-5H-[1,3]thiazolo[5',4':4,5]pyrrolo[2,3-d]pyridazin-5-one, MANGANESE (II) ION, ... Authors: Jin, L, Padyana, A. Deposit date: 2023-06-29 Release date: 2023-12-27 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure-Based Design of AG-946, a Pyruvate Kinase Activator. Chemmedchem, 19, 2024
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2023-06-29
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