five

Tankyrase-1 in complex with small molecule inhibitor

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Tankyrase-1 in complex with small molecule inhibitor Descriptor: 3-(4-methoxyphenyl)-5-({[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,2,4-oxadiazole, GLYCEROL, SULFATE ION, ... Authors: Kirby, C.A, Stams, T. Deposit date: 2011-10-28 Release date: 2012-02-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: [1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding. J.Med.Chem., 55, 2012
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2011-10-28
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