Huntington disease protein accelerates tumour development and metastasis

ChEBI2014-04-14 更新2026-07-21 收录

肿瘤生物学机制

疾病蛋白功能

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28685 数据链接链接失效反馈

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Huntington disease protein accelerates tumour development and metastasis

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2014-04-14

Nuclear protein (Nupr)-1 is required for pancreatic adenocarcinoma development in Pdx1-cre;LSL-KrasG12D;Ink4a/Arffl/fl mice

胰腺癌模型

肿瘤生物学机制

Nuclear Protein 1 (Nupr1) is a major actor of the cell stress response required for KrasG12D-driven formation of pancreatic intraepithelial neoplastic (PanINs) lesions in mice. We investigated the imp

NIAID Data Ecosystem70

Biology of human melanoma

黑色素瘤基因表达与功能

肿瘤生物学机制

In normal skin, interactions between melanocytes and keratinocytes, and between melanocytes and the basal membrane are functionally relevant for maintenance of homeostasis and epidermal melanin unit w

NIAID Data Ecosystem40

Lin28 increase chemotherapeutic drug resistance in gastric cancer.

化疗耐药性

肿瘤生物学机制

(A). Gastric cancer cell line MKN45 and MKN 28 with Lin28 overexpression were established via Lin28 plasmid transfection, Lin28 expression was detected by Western-blot.(B). mRNA level of Lin28 was det

NIAID Data Ecosystem30

Disrupting Circadian Homeostasis of Sympathetic Signaling Promotes Tumor Development in Mice

癌症昼夜节律

肿瘤生物学机制

BackgroundCell proliferation in all rapidly renewing mammalian tissues follows a circadian rhythm that is often disrupted in advanced-stage tumors. Epidemiologic studies have revealed a clear link bet

NIAID Data Ecosystem50

[Morphological and biological features of neoplasms: Integration of molecular findings]

肿瘤分子病理学

肿瘤生物学机制

Integration of morphologic and molecular findings in neoplasms (for details, please refer to Histopathology 2008; 53(1):1-19). Molecular definition of neoplasm and precursor lesions. Intraepithelial l

Figshare2016-01-12 更新30

Huntington disease protein accelerates tumour development and metastasis

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