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IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate M1-like macrophage polarization

NIAID Data Ecosystem2026-03-11 收录

细胞极化调控

干扰素γ信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE120945 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-09-19

细胞极化调控

差异表达miRNA分析

The goal of this experiment was to identify the differential expression of microRNAs in human polarised macrophages. We used monocyte-derived macrophages isolated from 8 different healthy invididuals.

NIAID Data Ecosystem40

data_sheet_1_Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression.docx

细胞极化调控

肿瘤免疫治疗靶点

The Notch pathway plays critical roles in the development and functional modulation of myeloid cells. Previous studies have demonstrated that Notch activation promotes M1 polarization and phagocytosis

NIAID Data Ecosystem30

Untitled ItemMechanical Stress Protects Against Chondrocyte Pyroptosis through Lipoxin A4 via Synovial Macrophage M2 Subtype Polarization in an Osteoarthritis Model

关节炎机制研究

细胞极化调控

Our previous study found that lipoxin A4 (LXA4) exerted therapeutic effects on osteoarthritis (OA). In this study, we evaluated the effects of LXA4 via synovial macrophage M1/M2 subtype polarization o

Figshare2022-05-17 更新20

Tanyu Tongzhi Formula regulates macrophage polarization

细胞极化调控

动脉粥样硬化药物

In previous study, we found TTF could regulate M2 polarization in the atherosclerotic plaque in ApoE-/- mice, but the underlying mechanism remains unknown. To detect the effect of TTF on RNA expressio

NIAID Data Ecosystem30

Data_Sheet_1_SHIP-1 Regulates Phagocytosis and M2 Polarization Through the PI3K/Akt–STAT5–Trib1 Circuit in Pseudomonas aeruginosa Infection.pdf

铜绿假单胞菌感染免疫机制

细胞极化调控

SHIP-1 is an inositol phosphatase that hydrolyzes phosphatidylinositol 3-kinase (PI3K) products and negatively regulates protein kinase B (Akt) activity, thereby modulating a variety of cellular proce

NIAID Data Ecosystem30

IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate M1-like macrophage polarization

资源简介：

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