tRF-394 has the potential to be a RNA-based therapy for H. pylori-infected gastric cancer

HGC-27 GC cells were stimulated with Helicobacter pylori-lipopolysaccharide (Hp-LPS). PANDORA-seq sequencing was employed to elucidate the potential roles of these relatively uncharacterized novel small non-coding RNAs (sncRNAs) in Hp-infected gastric cancers. RNA-seq was performed to identify diffferentially-expressed gene in Hp-infected gastric cancers. Overall design: PANDORA-Seq profiling of the GC cells after stimulated by H. pylori LPS compared with H. pylori-negative controls.