Initial starting points and converged calibrated parameters obtained from optimization.

The MultiStart option was utilized to define a set of feasible starting points and search for local minima for each point [81]. The algorithm successfully converged to solutions for three of the local solutions. While the starting points 2 and 3 were suggested by the solver, starting point 1 was determined through a trial-and-error approach involving multiple simulations and a sensitivity analysis (S3 Appendix).