When we designed the Valkyrie trial several different considerations were made on how to calculate the number of patients to be recruited for the trial. In the end, the decision fell on the way as des
Over-dispersed count variables are frequently encountered in biomedical research. Despite extensive research in analytical methods, addressing over-dispersion in the design of clinical trials has rece
Continuous outcomes sample size Stata do file. Stata do file to perform sample size calculations for continuous outcomes using formulae presented in the ‘Performing a sample size calculation’ section,
