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An Approach to the Core Skeleton of Lancifodilactone F

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NIAID Data Ecosystem2026-03-06 收录
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Two cycloaddition reactions were utilized for the construction of the 5,6,7-tricyclic skeleton of lancifodilactone F and buxapentalactone. A [2+2] ketene cycloaddition reaction was first used to set their adjacent all-carbon quaternary centers at the 5,6-ring junction. An arene−olefin meta-photocycloaddition reaction was then used to install the 6- and 7-membered rings concurrently.

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2016-06-03
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