Clinical study on heat-sensitive moxibustion for reducing toxicity and enhancing efficacy in adjuvant tumor chemotherapy

ObjectiveTo observe the clinical efficacy of heat-sensitive moxibustion in reducing toxicity and enhancing efficacy in cancer patients undergoing chemotherapy， and to provide a scientific basis for its application and promotion in cancer rehabilitation.MethodsA total of 150 malignant tumor patients were selected and randomly divided into a control group （75 cases， with 25 dropouts） and an experimental group （75 cases， with 21 dropouts）. The control group received conventional chemotherapy and pharmacological treatment， while the experimental group received additional heat-sensitive moxibustion treatment， which administered once daily for 1 week before and after each chemotherapy session， for 4 consecutive chemotherapy cycles. Evaluation indicators included the incidence of adverse reactions， anorexia/cachexia scale （A/CS-12）， nausea and vomiting grading， white blood cell count， platelet count， hemoglobin level， bone marrow suppression grade， and response evaluation criteria in solid tumors （RECIST 1.1）. Data were collected before and after each chemotherapy session and statistically analyzed.ResultsCompared with pre-chemotherapy levels， as the number of chemotherapy sessions was increased， A/CS-12 scores were decreased in both groups （PPPPPPPPnd to 4th chemotherapy sessions （PPrd and 4th sessions （PPConclusionHeat-sensitive moxibustion can reduce the incidence of chemotherapy-induced adverse reactions， alleviate gastrointestinal discomfort and bone marrow suppression， improve chemotherapy efficacy. It is worthy of clinical promotion and application.