Crystal Structure of SARS-CoV-2 Main Protease N142S mutant in complex with Nirmatrelvir
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal Structure of SARS-CoV-2 Main Protease N142S mutant in complex with Nirmatrelvir Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE Authors: Noske, G.D, Godoy, A.S, Oliva, G. Deposit date: 2022-08-14 Release date: 2022-10-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.845 Å) Cite: Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease. J.Biol.Chem., 299, 2023
创建时间：
2022-08-14
