The objective of this experiment was to compare the transcriptional profile of T cells modified to express CAR, TBBR and 4/7 ICR (i.e. SmarT-cells) against control 1G CAR T cells expressing CD3z endod
We report the transcriptomic and epigentic profile of human primary CD19-28z CAR-T cells. Overall design: CRISPR gene editing was used to delete MED12 or the "safe harbor" control gene AAVS1. Gene-edi
We report the transcriptomic and epigentic profile of human primary CD19-28z CAR-T cells. Overall design: CRISPR gene editing was used to delete MED12 or the "safe harbor" control gene AAVS1. Gene-edi
