Effect of BXL-01-0029 onto TNFα-treated Hfsmc.
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A, B, Western blot analysis was performed to assess JNK (A) and NF-kB (B) activation after 12 min stimulation with TNFα (10 ng/ml), with or without BXL-01-0029 (10−8 M). TNFα induced JNK and NF-kB phosphorylation; BXL-01-0029 impaired JNK activation and prevented NF-kB phosphorylation (upper A and B); total JNK and NF-kB were used as loading control (middle A and B). Lower A and B report densitometric analysis (*P#P−8 M). TNFα and BXL-01-0029 induced ERK1/2 phosphorylation (*P#P−8 M) after 24 h incubation; *P
创建时间：
2016-02-24
