Transcriptome data after TRIM28 knockdown in A375 melanoma cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133073
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TRIM28 is a bromodomain protein implicated in the regulation of tumor growth. TRIM28 regulates gene expression by recruiting epigenetic writers including HDACs, SETDB1 and HP1. To determine the role of TRIM28 in melanoma cells we knocked down TRIM28 using lentiviral shRNA constructs followed by gene expression analysis using HTA 2.0 GeneChip. Eight samples were analyzed. Four control samples (non-targeting control shRNA) and four experimental samples (TRIM28-specific shRNA).
创建时间:
2022-11-07



