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Investigating the effect of inflammatory conditions on acetaminophen-induced liver injury using 3D human multicellular microtissues

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NIAID Data Ecosystem2026-03-12 收录
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To investigate the molecular mechanisms of the inflammation-mediated exacerbation of increased acetaminophen (APAP) toxicity. 3D-co-cultured microtissues (MTs), consisting of primary human hepatocytes (PHH) and Kupffer cells (KCs), were exposed to 0, 0.5, 5 and 10 mM acetaminophen for 24h with/without lipopolysaccharide (LPS).

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2021-07-25
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