Global Analysis of Co-occurring Mutations in the SARS-CoV-2 Nucleocapsid Gene (n = 4,180,000 Genomes, 2022 - 2025)

This dataset identifies co-occurring mutation pairs in the SARS-CoV-2 nucleocapsid (N) gene across 4.18 million genomes from 2022 to 2025. It highlights persistent mutational linkages such as N:R203K+N:G204R and N:P13L+N:S413R, offering insights into viral evolution and genomic stability. Top 10 Co-occurring N Gene Mutations: 1- N:G204R N:R203K 5166585 2 N:P13L N:R203K 4393442 3 N:G204R N:P13L 4376088 4 N:P13L N:S413R 2872893 5 N:D377Y N:R203M 2859409 6 N:R203K N:S413R 2854079 7 N:G204R N:S413R 2833400 8 N:D63G N:R203M 2824945 9 N:D377Y N:D63G 2805255 10 N:G215C N:R203M 2685670 This work is part of the broader GVAtlas (gvatlas.org) initiative to track viral adaptation and support global surveillance. Data was derived from publicly available sequences, with gratitude to GISAID. Funding: This effort is part of open global health monitoring and receives no direct funding.