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Impact of Olfr78 Knockout on enteroendocrine cells and on colon homeostasis. Impact of Olfr78 Knockout on enteroendocrine cells and on colon homeostasis

NIAID Data Ecosystem2026-05-01 收录

肠道内分泌细胞

结肠稳态

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA956254 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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创建时间：

2023-04-16

肠道内分泌细胞

单细胞转录组学

Homeostatic regulation of the intestinal enteroendocrine lineage hierarchy is a poorly understood process. We resolved transcriptional changes during enteroendocrine differentiation in real-time at si

NIAID Data Ecosystem90

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

结肠稳态

结肠肿瘤

We report the gene expression differences in the colonic epithelium of control and Ehf knockout mice assessed by RNA-seq analysis. Overall design: We performed RNA-seq analysis of colonic epithelial c

NIAID Data Ecosystem80

Human intestinal organoid cell transcriptomic profiling

肠道内分泌细胞

转录组学分析

We purified two populations of human ileal enteroendocrine cells (Venus+ and Venus-) from mature differentiated hGLU-Venus organoids by FACS and identified transcripts enriched in endocrine cell linea

NIAID Data Ecosystem50

Loss of cyclin A2 in murine colonic epithelial cells disrupts colon homeostasis by triggering DNA damage and dysplasia and high cyclin A2 expression is a good-prognosis factor in patients with colorectal cancer. Loss of cyclin A2 in murine colonic epithelial cells disrupts colon homeostasis by triggering DNA damage and dysplasia and high cyclin A2 expression is a good-prognosis factor in patients with colorectal cancer

结肠稳态

结直肠癌预后标志物

To clarify the function of cyclin A2 in colon homeostasis and colorectal cancer (CRC) we generated mice deficient for cyclin A2 in colonic epithelial cells (CEC). Colons of those mice displayed archit

NIAID Data Ecosystem80

Enteroendocrine cell types that drive food reward and aversion. Enteroendocrine cell types that drive food reward and aversion

肠道内分泌细胞

食物学习行为

Animals must learn through experience which foods are nutritious and should be consumed, and which are toxic and should be avoided. Enteroendocrine cells (EECs) are the principal chemosensors in the G

NIAID Data Ecosystem60

Impact of Olfr78 Knockout on enteroendocrine cells and on colon homeostasis. Impact of Olfr78 Knockout on enteroendocrine cells and on colon homeostasis

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