Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.

Data from ProteomeXchange, PXD ID: PXD001323. Experiment: hmf_cyt_TGFb_1, file: hmf_cyt_TGFb_1_2.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue proteome profiling. Tissue proteomics was performed on tumor-central, tumor-near and tumor-distant biopsy sections from breast adenocarcinoma patients, which allowed us to identify 2074 proteins ... {{/i}}