five

True positives predictions.

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Figshare2015-12-02 更新2026-04-29 收录
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Using a p-value cutoff of 0.01, 50 pairs of kinases are predicted to share inhibitors. Nine pairs have experimental evidence suggesting overlap in inhibitor binding- these are true positives. The first two columns are EC groups. Kinases in one pair are from different EC groups. The PDB IDs and gene names are listed in column three to row six. The seventh column lists the percentage identity (PID) of structural alignment between two kinases in a pair. The eighth column shows the binding site similarity score of the pair. The more negative the score is, the higher the similarity level between two sites is predicted.
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2015-12-02
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