Detailed patient characteristics and tumor mutation status.

DNA was extracted from 97 tissue biopsies and 105 biopsy-derived cell lines from 109 metastatic melanoma patients, and screened for mutations in exons 11 and 15 of the B-RAF gene and exons 1 and 2 of the N-RAS gene. AJCC, American Joint Committee on Cancer; NM, nodular melanoma; SSM, superficial spreading melanoma; ALM, acrolentiginous melanoma; LMM, lentigo maligna melanoma; occult, melanoma of unknown primary; C/SQ, cutaneous or subcutaneous metastasis; LN, lymph node metastasis; wt, wildtype; n.a., not available; n.d., not done.