Improvements in Methyl-Bambus[6]uril Synthesis Yield

Bambus[n]uril synthesis may be challenging, and it is frequently achieved with low purity and low yields. We have studied the effect of different anions on the synthesis of bambus[6]uril, especially in terms of yield, exploring template effects driven by anions in the reaction medium. The influence of the anions is evident on such syntheses and ClO4− particularly led to unprecedented synthesis yields. Computational calculations have also been used to elucidate the influence of anions on cyclization process.