Sub-THz Vibrational Mode Spectrum of the α/β-Tubulin Dimer (1TUB) via Anisotropic Network Model

A reproducible, deterministic elastic-network normal-mode spectrum of the canonicalmicrotubule building block (PDB 1TUB) in the sub-terahertz band. The tubulin dimer is reducedto an 867-CA anisotropic network model (cutoff 13 Å), the 2601×2601 Hessian is fullydiagonalized, and all 2,595 non-rigid modes are reported with eigenvalue, relative frequency,and approximate THz value, plus per-CA displacement vectors for the lowest 20 mode shapes. Theslowest collective mode sits at ≈0.10 THz; the full band spans ≈0.10–1.88 THz. Rigid-bodysanity check passed (first 6 eigenvalues ≈0, ≤1.8e-14). **Honest scope (do not inflate):** Relative spectrum and mode ordering are robust(geometry-determined, calibration-free); absolute THz scales as √γ and is order-of-magnitudeonly. ANM/ENM of tubulin is an *established method, not novel* — the contribution is a clean,reproducible, openly-deposited spectrum + mode-shape feature set for the canonical dimer,framed as a dataset/method record, NOT a discovery. No matched-random control vs anon-microtubule protein was run; do not claim the profile is "special."