Transcriptomic analysis in the CD45- adipocytes ,CD45+ adipocytes differentiated in vitro

Brown adipose tissue (BAT) plays an important role in maintaining body temperature in mammals after birth, however, the mechanism of adipocytes subpopulations remains poor understood. Here we report the identification of a special population of brown adipose tissue-derived stromal cells (ASCs) in neonatal mice that highly express CD45, which can be differentiated into adipocytes but with lower expression levels of thermogenic genes compared to traditional brown adipocytes.