Reactivity Data

Reactivity profiles for MS2 RNA which has undergone X-ray footprinting in transcript, in virio, post extraction and post reassembly.footprinted samples have been processed using capillary electrophoresis (CE) and the CE traces have been analysed using the BoXFP software package. Each file contains 3 columns; the first details the positions of the datapoints in the MS2 genome; the second column contains the average reactivity values; the third column contains the standard errors on the mean for the reactivity values. The files ending reacs.csv contains the unnormalised reactivity profiles whilst those ending reacsNorm.csv contain the normalised reactivity profiles. The primer used, treatment condition, and X-ray exposure time is also provided in the label of the files. Note that all profiles have been corrected against background samples (0 ms exposed samples). means and standard errors on the mean are taken over 3 replicates excepted for the primer 6 Virion and Reassembled samples which are over two replicates.