Efficient and Regioselective Synthesis of Novel Functionalized Dispiropyrrolidines and Their Cytotoxic Activities
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https://figshare.com/articles/dataset/Efficient_and_Regioselective_Synthesis_of_Novel_Functionalized_Dispiropyrrolidines_and_Their_Cytotoxic_Activities/2316418
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资源简介:
An efficient and regioselective synthesis
of novel functionalized
dispiropyrrolizidine derivatives via a three-component [3 + 2] cycloaddition
reaction of azomethine ylides is described. This protocol has the
advantages of high efficiency, mild reaction conditions, a one-pot
procedure, and convenient operation. Many of these compounds were
evaluated for their antiproliferative properties in vitro against
cancer cells and several compounds were found to have good activities.
创建时间:
2014-03-10



