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Beta cell dysfunction and identity loss induced by low dose of Interleukin-1β is associated with changes in histone acetylation and gene expression [ChIP-seq]. Beta cell dysfunction and identity loss induced by low dose of Interleukin-1β is associated with changes in histone acetylation and gene expression [ChIP-seq]

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NIAID Data Ecosystem2026-03-10 收录
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We report maturity loss and dysfunction of primary mouse islets exposed to prolonged low Interleukin-1B exposure is associated with a decreassed expresion of key beta cell genes and a decreased H3K27ac mark Overall design: Examination of 3 histone modifications (H3K27ac; H3K27me3 and H3K4me3) in primary mouse islets exposed or non-exposed to Interleukin-1B for 10 days

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2018-02-15
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