Low Microfilaremia Levels in Three Districts in Coastal Ghana with at Least 16 Years of Mass Drug Administration and Persistent Transmission of Lymphatic Filariasis - Ghana

Geographic coverage --------------------------- 18 LF endemic villages in the AhantaWest, Nzema East and Ellembele Districts in the Western Region of Ghana Kind of data --------------------------- sample survey data[ssd] Sampling procedure --------------------------- Study sites were selected following a review of the Neglected Tropical Disease Programme (NTDP) sentinel and spot check site monitoring data, as well as recommendation from the District Health Management Team (DHMT). The sample size determination took into consideration the null hypothesis that an additional MDA is not more effective than the standard single dose per annum treatment, and the alternate hypothesis that an additional MDA is more effective than the standard single dose. With prevalence between sites ranging from 1% to 18%, the sample size was determined assuming an effect size of 0.4, power of 0.80, 37% non-response rate (determined from a previous study). Thus, 80 participants were targeted from each community, with a total of 1440 participants for the entire study. Mode of data collection --------------------------- A computer-assisted personal interviewing (CAPI) ,