Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4

Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4 Descriptor: 5-[methyl-[(2-propoxypyridin-3-yl)methyl]amino]-2~{H}-indazole-3-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 Authors: Ferguson, A.D. Deposit date: 2020-03-10 Release date: 2021-05-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021HAO1与吲唑酸类抑制剂——化合物4的共晶晶体结构 组分：5-[甲基-[(2-丙氧基吡啶-3-基)甲基]氨基]-2H-吲唑-3-羧酸、黄素单核苷酸（FLAVIN MONONUCLEOTIDE）、羟酸氧化酶1（Hydroxyacid oxidase 1, HAO1） 作者：Ferguson, A.D. 沉积日期：2020-03-10 发布日期：2021-05-12 最后修改日期：2023-10-18 测试方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.64埃 引用文献：《利用DNA编码化学文库筛选发现强效新型羟酸氧化酶1（HAO1）抑制剂》，《药物化学杂志》，2021年，第64卷