NMR based Metabolomics Analysis Revealed Elevated Acetate and Acetate-to-urea ratio in Peritoneal Dialysis Effluent of Bacterial Peritonitis Patients

This dataset contains the raw and processed ¹H NMR spectral data acquired from peritoneal dialysis effluent samples collected from a patient with bacterial peritonitis and from non-infected controls. The study aimed to characterize metabolic alterations associated with bacterial infection in peritoneal dialysis patients using NMR-based metabolomics. A total of 39 PD effluent samples were analyzed, comprising 20 episodes from 10 normal PD patients (non-infected controls) and 19 episodes from 12 PD patients suspected of bacterial peritonitis (BP). All NMR spectra were acquired at 298 K on a Bruker Avance III 800 MHz spectrometer equipped with a Cryoprobe, using standard Bruker pulse programs. One‐dimensional 1H‐NMR spectra of all PD effluent samples were collected with the Carr-Purcell-Meiboom-Gill (CPMG) pulse sequence (cpmgpr1d) incorporating water suppression by pre-saturation.