Single-cell RNA/ATAC multiomic analysis of TRM and ReCirulating CD8+ T cells from HGSOC tumors. Single-cell RNA/ATAC multiomic analysis of TRM and ReCirulating CD8+ T cells from HGSOC tumors

Purpose: Evaluation of the BCR profile of HGSOC associated/infiltrated B cells Overall design: We isolated TRM and ReCirulating CD8+ T cells from X HGSOC disscociated tumors and performed 10X Multiome ATAC + Gene Expression

搜集汇总

背景与挑战

背景概述

该数据集通过单细胞RNA测序和ATAC测序多组学技术，分析了来自高级别浆液性卵巢癌（HGSOC）肿瘤中的组织驻留记忆（TRM）和再循环CD8+ T细胞，旨在探究其免疫特征和BCR谱。研究是“卵巢癌免疫原性由窄谱系祖细胞组织驻留记忆T细胞调控”项目的一部分，相关数据已发表并提供16个SRA实验样本。