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Diurnal transcriptome of adult zebrafish eye

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NIAID Data Ecosystem2026-03-10 收录
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Circadian rhythms orchestrate organism physiology to rhythmic changes in the environment, with the daily day and night cycle being the most prominent cyclic change occurring. In this regard, retina being a light responsive organ shows its vital physiological processes to be regulated by the clock. Here we report the diurnal transcriptome of zebrafish retina at Zt4(day) and Zt16(night). We found 39% and 31% of the known genes to be expressed in retina at Zt4 and Zt16 respectively (Reference genome-Zv9). Also, by applying stringent cutoff of 5FPKM we identified 123 transcripts to be expressed differentially between the two-time points, which contains few novel transcripts. In future, this study will contribute to the understanding of organ and species specific regulation of circadian rhythms and will also provide novel genes involved in the circadian regulation of retina.

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2018-08-10
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