Blood Illumina Inf 450 DNA methylation samples from HIV+ and HIV- human subjects

Genome wide DNA methylation profiles of cerebellum from HIV positive and HIV negative human subjects. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 486,000 CpGs. Dataset included 92 subjects from the USA. The epigenetic clock software (Horvath 2013) was used to measure epigenetic age acceleration effects and to relate them to HIV status. Bisulphite converted DNA from the 92 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip. HIV-1 status was related to an epigenetic measure of age acceleration.