five

GSE44742: Genetic differences underlying chromatin discordance between monozygotic twins

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP019225
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Summary: Open chromatin is implicated in regulatory processes, and thus variation in chromatin structure may contribute to variation in gene expression and other molecular phenotypes. In this work, we performed a targeted deep sequencing to identify somatic mutations and genetic polymorphisms underlying accessible chromatin in the genomes of 72 monozygotic twins. Overall Design: Open chromatin sequencing based on FAIRE assay for 36 pairs of monozygotic twins
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2021-09-21
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