Effect of the 4-1BB-4/1BBL interaction on allogeneic and syngeneic concepti.
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Wild-type or 4-1BB-deficient female mice in a C57BL/6 background (8 weeks-old) were mated with syngeneic C57BL/6 or allogeneic DBA/2 males. Control rat IgG, blocking anti-4-1BBL mAb (TKS-1) or agonistic anti-4-1BB (3E1) was injected i.p. into the mice at 200 µg per mouse 8, 10, and 12 days after mating. Data are means ± SD. P values are calculated relative to the rat IgG-treated controls: ***P<0.0001.
创建时间:
2012-09-21



