Engineering protein stability with atomic precision in a monomeric miniprotein

NIAID Data Ecosystem2026-05-02 收录

蛋白质稳定性工程

单体微小蛋白设计

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Engineering protein stability with atomic precision in a monomeric miniprotein

创建时间：

2024-11-06

Extremely stable monomeric variant of human cystatin C with single amino acid substitution

蛋白质稳定性工程

蛋白质结构解析

Extremely stable monomeric variant of human cystatin C with single amino acid substitution Descriptor: Cystatin-C Authors: Zhukov, I, Rodziewicz-Motowidlo, S, Maszota-Zieleniak, M, Jurczak, P, Kozak,

Protein Data Bank Japan2024-11-13 更新60

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

胰岛素类似物

蛋白质稳定性工程

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein Descriptor: Single-chain insulin analog Authors: Ye

Protein Data Bank Japan2024-11-06 更新20

LARGE INCREASES IN GENERAL STABILITY FOR SUBTILISIN BPN(PRIME) THROUGH INCREMENTAL CHANGES IN THE FREE ENERGY OF UNFOLDING

蛋白质稳定性工程

酶热力学优化

LARGE INCREASES IN GENERAL STABILITY FOR SUBTILISIN BPN(PRIME) THROUGH INCREMENTAL CHANGES IN THE FREE ENERGY OF UNFOLDING

NIAID Data Ecosystem10

Stabilization of PYR1 Biosensors by GMMA

生物传感器

蛋白质稳定性工程

Functional screens were used in conjunction with GMMA to identify universally stabilizing mutations for the biosensor PYR1.

NIAID Data Ecosystem40

Stabilizing proteins through saturation suppressor mutagenesis

蛋白质稳定性工程

饱和抑制突变筛选

Purpose: The goals of this study is to reconstruct expression and binding MFI of each mutant in a second-site saturation suppressor mutagenesis library of CcdB. the reconstructed MFI was to identify b

NIAID Data Ecosystem10

Engineering protein stability with atomic precision in a monomeric miniprotein

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