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Lipid signalling enforces functional specialization of Treg cells in tumours [scRNA-seq EAE]

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NIAID Data Ecosystem2026-03-12 收录
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Metabolic reprogramming enforces Treg cell functional specialization in tumors by coordinating fatty acid biosynthesis and inhibitory receptor signaling pathways. These findings point to new avenues to selectively targeting intratumoral Treg cells for cancer therapy. Overall design: We used scRNA-seq to compare Treg cells from spleen and CNS in EAE mouse model

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2021-03-02
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