“TKO” is an expression vector that knocks out the activity of a transcription factor in vivo under genetic control. We describe a successful test of this concept that used a sea urchin transcription f
This dataset consists of RNA-seq data data from human monocytes, monocyte-derived dendritic cells or monocyte-derived macrophages as well as monocyte-derived cells that were subjected to siRNA treatme
Adaptation to diverse transcription factor knockouts reveals robustness of transcription regulatory network Overall design: To investigate impact of TF KO's on the transcriptome, TF's were KO'd and ev
