Transcriptome analysis of inflammation-related gene expression in endothelial cells activated by complement MASP-1
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE98114
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资源简介:
Transcriptional profiling of human umbilical vein endothelial cells, treated with MASP-1, thrombin, LPS, histamine, TNFalpha, MASP-1+SB203580 (p38-MAPK inhibitor) or MASP-1+Bay-117082 (NFKB inhibitor). Goal was to determine the effect of MASP-1 on HUVECs, to compare this with the effect of other endothelial cell activators and to determine the MASP-1 induced signalling pathways. Two-color microarray experiment, with several different treatments. 13 samples were analyzed. 2h MASP-1 treatment: 4 biological replicates; TNFalpha treatment: 2 replicates; 1h MASP-1, 6h MASP-1, LPS, histamine, thrombin, SB203580, Bay-117082 treatment: 1-1 replicate
创建时间:
2024-05-01



