Analogues of radicicol bound to the ATP-binding site of Hsp90.
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Analogues of radicicol bound to the ATP-binding site of Hsp90. Descriptor: (5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Authors: Roe, S.M, Prodromou, C, Pearl, L.H. Deposit date: 2006-07-05 Release date: 2006-11-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Inhibition of Hsp90 with Synthetic Macrolactones: Synthesis and Structural and Biological Evaluation of Ring and Conformational Analogs of Radicicol. Chem.Biol., 13, 2006
创建时间：
2006-07-05
