Steroid receptor coactivator 3 is a key modulator of regulatory T cell–mediated tumor evasionT Cells

SMART-seq analysis is used for single cells or for a small amount of purified total RNA from low number of cells. The goal of this study to compare the quantitative differences between the SRC-3+ and SRC-3-/- Tregs cell transcriptomes. Transcriptome differences between WT and SRC-3KO Tregs explored to explain the anti-tumor effects of SRC-3KO Tregs