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YAP and RUNX co-regulated genes in MCF10A

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60876
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An antagonistic interplay between YAP and RUNX where RUNX proteins abrogate YAP-mediated transcription of EMT and Stemness associated genes in mammary epithelial cells in an interaction dependent manner. YAP and RUNX1 or RUNX3 were stably expressed together or alone in MCF10A cell line. Genes that are co-regulated by both were studied in the context of breast cancer.
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2018-07-26
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