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Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1198

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Protein Data Bank Japan2024-05-22 更新2026-03-21 收录
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Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1198 Descriptor: 1,2-ETHANEDIOL, 1-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)piperidine-4-carboxylic acid, Dihydrofolate reductase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-20 Release date: 2022-02-09 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1198 to be published

结核分枝杆菌(Mycobacterium tuberculosis)结合NADP与SDDC抑制剂SDDC-1198的二氢叶酸还原酶(Dihydrofolate Reductase)晶体结构 描述项:1,2-乙二醇、1-(2-{3-[(2,4-二氨基-6-乙基嘧啶-5-基)氧基]丙氧基}苯基)哌啶-4-羧酸、二氢叶酸还原酶等 作者:西雅图传染病结构基因组学中心(Seattle Structural Genomics Center for Infectious Disease,缩写SSGCID) 提交日期:2021-12-20 发布日期:2022-02-09 最后修改日期:2024-05-22 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.4埃 引用说明:结核分枝杆菌结合NADP与SDDC抑制剂SDDC-1198的二氢叶酸还原酶晶体结构,待发表
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2021-12-20
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