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p53-inducible lncRNA LOC644656 causes genotoxic stress-induced stem cell maldifferentiation and cancer chemoresistance

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP012217
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资源简介:
Genotoxic stress-induced stem cell differentiation is a protective mechanism in response to cell death. Herein, LOC644656 was identified as a p53-induced lncRNA that accumulates in the nuclei of human embryonic stem cells (hESCs) following genotoxic stress-induced maldifferentiation. We performed multi-omics analyses and identified LOC644656 functions in hESCs and cancer cell lines.
创建时间:
2025-07-03
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