These mass spec data refer to Figures 5A of our manuscript PARP-inhibition reprograms macrophages towards an anti-tumor phenotype; CELL-REPORTS-D-21-05754R2
PARP inhibitors (PARPi) are thought to control cancer cell growth by inducing syntheticlethality with DNA repair defects (e.g., in BRCA1/2 mutant cells). We have identified an alternate pathway for PA
Recently, poly(ADP-ribosyl)ation polymerase inhibitors (PARPis), which induce synthetic lethality of tumor cells with DNA damage repair defects, have emerged as a promising therapy for ovarian, breast
Introduction: Breast cancer is the second most common cause of central nervous system (CNS) metastases. It has been shown that the median time from breast cancer diagnosis to CNS metastasis is 30.9 mo