Colonic bacterial composition is sex-specific in aged CD-1 mice fed diets varying in fat quality

Two cohorts of CD-1 mice, each from a different animal husbandry facility, were fed isoenergetic, high-fat diets (40% kcal) of either (1) control fat (CO; “Western-style” fat blend), (2) FO: CO supplemented with 30% fish oil, (3) BO: CO supplemented with 30% dairy fat, or (4) EO: CO supplemented with 30% echium oil until 14 months of age. In addition, a group of male mice was fed laboratory chow (14% kcal fat). From one cohort, fecal samples were collected at 9 months of age. From a second cohort, fecal samples were collected at 10.5 and 13.5 months of age.