SAPK/JNK Signaling
收藏NIAID Data Ecosystem2026-05-10 收录
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Stress-activated protein kinases/c-Jun NH(2)-terminal kinases (SAPK/JNK) proteins are MAPK family members that are activated by several extracellular signals (i.e. inflammatory cytokines and growth factors) and cellular stress. When activated by cellular stress the SAPK/JNK pathway induces cell death by apoptosis. The SAPK/JNK pathway also plays a physiological role in embryonic development by regulating cell survival, apoptosis, and proliferation.
创建时间：
2025-11-26
