HLA haplotype and CD risk.

p values in boldface are significant aX = any HLA-DQB1 allele different from *02 or *0302 bOR = Odds Ratio; 95%CI = 95% Confidence Intervals. Odds Ratios were calculated by binary logistic regression analysis adjusted for age, gender and H. pylori infection c Risk of CD is expressed as 1:N, where N is the number of individuals among which one case is present. Considering a disease prevalence of 1:184 in the general population [37], for each HLA-DQ category, N is calculated as a percentage of controls with that particular HLA-DQ status multiplied by 184 and divided by percentage of patients with the same DQ typing [10]. HLA haplotype and CD risk.